The history of botox (and many curiosities about botulinum toxin)

What lifts the wrinkles, what erases them, eliminates them, relaxes the features, freezes the muscles by sending back the hands of time? In everyone’s mind, only one word is revealed, five letters: botox. Loved by many celebs and mere mortals but also criticized, not understood, it is actually relatively safe, with few negative effects. We tried to dismantle prejudices and so-called “false myths” that surround the world of aesthetic medicine and that could lead to bad choices.

And to think that it all began with a sausage …

BOTOX, THE ORIGINS
Botulinum toxin takes its name from the Latin “botulus” which means “sausage”. In fact, it is by studying the causes of food poisoning following a wedding banquet during which sausages were eaten that, in 1820, the romantic poet and medical officer of the town of Welzheim in Germany, Justinius Kerner, coined this name, providing for first a clinical description of botulism. However, we owe to a Canadian ophthalmologist, Jean Carruthers, the cosmetic use of botox that by chance in the 1980s he found himself observing a reduction in the wrinkles of a patient’s forehead (a few years earlier, botulinum toxin had been approved to treat patients with strabismus and blepharospasm). The doctor shared this discovery with her dermatologist husband, Alastair, and the spouses published their first work onapplication of botulinum toxin for aesthetic use in 1996. The couple’s discovery, which later became a billion dollar industry, literally changed the face of beauty.

NEVER AGAIN WITHOUT AESTHETIC
Originally called Oculinum, the botox (botulinum toxin type A) we know today acquired its world-famous name from scientific director Mitchell Brin when pharmaceutical company Allergan bought the rights to it in 1989. Anyhow it was only in 2001 that botox received its first aesthetic medical approval in Argentina for the treatment of wrinkles between the eyebrows. Since then, botulinum toxin has gone a long way and it is now approved for 35 indications in approximately 97 countries worldwide. From 1995 to today, the numbers are record-breaking: more than 100 million vials of botox have been distributed throughout the world, which, however, is still divided between those in favor and the “retro Satan”. We recall that botulinum toxin is one of the most powerful poisons, so much so that we tried to use it at the beginning of the last century for war purposes, but even if in a highly elaborated, highly purified and injectable form it could really kill, “Beverly’s goal Hills would be dead, ”said dermatologist Ava Shamban ad Allure. So, just rely on expert hands (beware of charlatans, you must always inquire carefully and contact competent doctors). In addition, injectable techniques have refined over the past few years.

One last curiosity: botox is feminist. It costs men more than women to do this (at least this!) As male facial muscles are stronger and require double the amount of injectable to achieve a certain result. And this is the story of how botox has gone from being a poorly studied toxin to a successful drug which millions of people use today.

In the gallery the anti-aging cosmetics that mimic the effect. Why, after all, who doesn’t like to resort to elixirs of youth?

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