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WHO recommends the use of two monoclonal antibody preparations for the treatment of Ebola

The World Health Organization today recommended the use of two monoclonal antibody drugs against Ebola, saying the administration of these drugs combined with better care have revolutionized “the treatment of a disease once thought to cause almost certain death.”

It is the first time that the Ministry of Health has made recommendations for treatments to deal with Ebola.

The drugs — Regeneron’s Inmazeb and Ridgeback’s Ebanga (mAb114) — use lab-made monoclonal antibodies that mimic natural antibodies to fight infections.

“Advances in supportive care and pharmacotherapeutics over the past decade have revolutionized the treatment of Ebola. Ebola virus disease was once thought to cause almost certain death. But that is no longer the case,” said Robert Fowler, a professor at the University of Toronto. of Canada and co-chair of the WHO guideline development group. Effective care and the use of these medications now lead to the recovery of the “vast majority” of people from Ebola, he said, without giving specifics.

The new recommendations follow trials of dengue drugs in the Democratic Republic of Congo during the 2018-2020 outbreak there. Dr. Janet Diaz, head of the clinical management unit of the WHO’s Health Emergencies program, told reporters that the drugs are now available in DR Congo, but more work needs to be done to improve access.

“Access roads are a priority for work right now,” he said.

Source: AMPE

Source: Capital

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